Hi David,
Hope your had a very nice vacation
It`s too soon to see any changes and also to have a improvement in your EF, normally it takes about one sometimes two years.
Firts your feeling better and later on your cardiologist can also see the changes.
What you can add is, D-Ribose 12 gr. a day (powder)
Coronary Heart Disease (CHD) typically begins when, for one reason or another, the heart is unable to get the proper supply of blood, oxygen, energy or some combination of the three. Because the heart is a muscle and muscles need oxygen and energy in order to repair/rebuild themselves, it is of utmost importance to make sure your heart is getting the energy it needs.
Whether you suffer from CHD or just want to maintain good heart health, you should consider supplementing your diet with Wellness Partners RiboPure Crystals.
Who needs supplemental ribose?
Everyone needs ribose. It is an essential ingredient in stimulating natural energy production. Research has shown that ribose promotes cardiovascular health, reduces cardiac stress associated with strenuous activity and helps athletes reach new heights. Ribose helps hearts and muscles maximize energy recovery. Whether you are a trained athlete, a weekend warrior or are concerned about your cardiovascular health, ribose may help give the energy boost your body needs.
What will ribose do for someone concerned about cardiovascular health?
Numerous medical studies have shown that energy levels in the heart can be dramatically lowered by exercise or decreased blood flow associated with certain cardiac diseases. Depleted cardiac energy pools may be associated with increased cardiac stress, reduced blood flow to the periphery of the body, fatigue and decreased exercise tolerance. Ribose is the key nutrient for quickly restoring cardiac energy stores.
Recovery For Your Heart
Clinical and laboratory studies on the hearts of both animals and humans have shown many positive benefits of ribose including ventricular function (that is -- how well the heart is pumping blood) and enhanced recovery of energy-carrying nucleotide levels following ischemia (that is -- a lack of oxygen to tissues), and increased abililty to tolerate exercise in patients with stable coronary artery disease.
Low Blood Flow
When the flow of blood to the heart is impeded, it results in a substantial lowering of tissue energy. We know that this is the case because we see a decrease in the level of ATP (energy) in the heart tissues. With less energy comes a less efficient heart.2,3
Because this situation can occur in patients experiencing heart problems as well as those recovering from a surgical procedure where the blood flow was stopped for an extended period of time, researchers have been looking for ways to provide energy to the tissues in the form of a supplement.
In a series of oxygen depletion studies it was found that the process the body goes through to synthesize energy for the cells was impaired greatly.12,13,24,25 By providing ribose to the heart, the process of synthesizing energy is stimulated. The presence of ribose allows the body to skip several steps in the synthesizing process, leading to the production of PRPP.
This increase in PRPP levels is noted to be accompanied by accelerated cardiac adenine nucleotide synthesis and improved global heart function. Thus, ribose restores cardiac energy reserves and positively affects myocardial function.
Coronary Heart Disease and Exercise
The effect of orally-administered ribose on exercise tolerance in stable coronary artery disease patients has also been studied.26 Patients were randomized into two groups. Ten patients received placebo (glucose) for three days and another 10 patients received ribose dissolved in water for the same time period. A treadmill evaluation was performed in all patients after taking the supplement.
In the ribose-treated group, the mean walking time to the exercise threshold was significantly greater than in the placebo group (p < 0.002). The time to both the threshold and the onset of moderate angina was also prolonged significantly in the ribose group compared to its pre-ribose baseline (p<0.005).
These results show that patients who had been given ribose were able to exercise longer without chest pain or evidence of ischemia than patients who did not receive ribose.
Ribose and Cardiomyopathy
Another research study reported that ribose infusion in conjunction with dobutamine stress echocardiography increases the contractile response in hibernating regions of the heart.31 In a placebo-controlled double-blind study twenty-five patients with ischemic cardiomyopathy were infused with either D-ribose or dextrose placebo for the 4 hours prior to dobutamine stress echocardiography.
On day two the patients were crossed over to the alternate treatment. During dobutamine stress echocardiography more dysfunctional wall segments responded with improved wall motion when D-ribose was infused prior to the procedure as compared to placebo (p = 0.02). In patients who then underwent coronary artery bypass surgery the predictive sensitivity for functional recovery of the segments identified during the D-ribose infusion was greater than those identified during placebo infusion.
A recent review provides the background and rationale for the use of ribose in metabolic support of the heart.32 Evidence such as that discussed above is presented in support of the main hypothesis that ribose is the rate-limiting component (that is -- one with the ability to bypass several steps in the synthesis of energy) in the pathways necessary for the heart to restore depleted adenine nucleotide levels.
greetings,
Corrij